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St. Jude Unlocks Mystery of Very Aggressive Leukemia
Loss of Arf gene in acute lymphoblastic leukemia makes some forms of this cancer resistant to treatment with imatinib, but blocking JAK kinases can restore the sensitivity of cells to this drug.
SGX Pharmaceuticals Announces Strategic Collaboration To Develop And Commercialize BCR-ABL Inhibitor
SGX Pharmaceuticals, Inc. (NASDAQ:SGXP) has announced that it has entered into a license and collaboration agreement with Novartis focused on the development and commercialization of BCR-ABL inhibitors for the treatment of drug resistant Chronic Myelogenous Leukemia (CML).
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